Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells.

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Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells

Properties of the whole-cell K+ currents and voltage-dependent activation and inactivation properties of single K+ channels in clonal pheochromocytoma (PC-12) cells were studied using the patch-clamp recording technique. Depolarizing pulses elicited slowly inactivating whole-cell K+ currents, which were blocked by external application of tetraethylammonium+, 4-aminopyridine, and quinidine. The ...

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Gating kinetics of four classes of voltage-dependent K+ channels in pheochromocytoma cells

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1988

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.91.1.73